Compile Data Set for Download or QSAR
Found 7 of Enz. Inhib. data with enzyme = 'Beta-secretase 2' and Substrate = 'BACE Substrate Peptide'
TargetBeta-secretase 2(Homo sapiens (Human))
Merck Research Laboratories

LigandPNGBDBM16409(1-N-[(2S,3R)-4-(cyclopropylamino)-3-hydroxy-1-phen...)copy SMILEScopy InChI
Affinity DataIC50: 69nMpH: 4.5 T: 2°CAssay Description:The assay was performed using a 96-well format on a HPLC equipped with four 96-well plate holders. Test compounds were preincubated with enzymes for ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2XD0ZXTPubMed
TargetBeta-secretase 2(Homo sapiens (Human))
Merck Research Laboratories

LigandPNGBDBM16414(1-N-[(2S,3R)-4-(cyclopropylamino)-3-hydroxy-1-phen...)copy SMILEScopy InChI
Affinity DataIC50: 110nMpH: 4.5 T: 2°CAssay Description:The assay was performed using a 96-well format on a HPLC equipped with four 96-well plate holders. Test compounds were preincubated with enzymes for ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2XD0ZXTPubMed
TargetBeta-secretase 2(Homo sapiens (Human))
Merck Research Laboratories

LigandPNGBDBM16408(1-N-[(2S,3R)-4-(cyclopropylamino)-3-hydroxy-1-phen...)copy SMILEScopy InChI
Affinity DataIC50: 210nMpH: 4.5 T: 2°CAssay Description:The assay was performed using a 96-well format on a HPLC equipped with four 96-well plate holders. Test compounds were preincubated with enzymes for ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2XD0ZXTPubMed
TargetBeta-secretase 2(Homo sapiens (Human))
Merck Research Laboratories

LigandPNGBDBM16034(1-N-[(2S,3R)-4-(cyclopropylamino)-3-hydroxy-1-phen...)copy SMILEScopy InChI
Affinity DataIC50: 230nMpH: 4.5 T: 2°CAssay Description:The assay was performed using a 96-well format on a HPLC equipped with four 96-well plate holders. Test compounds were preincubated with enzymes for ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2XD0ZXTPubMed
TargetBeta-secretase 2(Homo sapiens (Human))
Merck Research Laboratories

LigandPNGBDBM16411(1-N-[(2S,3R)-4-(ethylamino)-3-hydroxy-1-phenylbuta...)copy SMILEScopy InChI
Affinity DataIC50: 260nMpH: 4.5 T: 2°CAssay Description:The assay was performed using a 96-well format on a HPLC equipped with four 96-well plate holders. Test compounds were preincubated with enzymes for ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2XD0ZXTPubMed
TargetBeta-secretase 2(Homo sapiens (Human))
Merck Research Laboratories

LigandPNGBDBM16413(1-N-[(2S,3R)-4-(cyclopropylamino)-3-hydroxy-1-phen...)copy SMILEScopy InChI
Affinity DataIC50: 360nMpH: 4.5 T: 2°CAssay Description:The assay was performed using a 96-well format on a HPLC equipped with four 96-well plate holders. Test compounds were preincubated with enzymes for ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2XD0ZXTPubMed
TargetBeta-secretase 2(Homo sapiens (Human))
Merck Research Laboratories

LigandPNGBDBM16410(1-N-[(2S,3R)-4-amino-3-hydroxy-1-phenylbutan-2-yl]...)copy SMILEScopy InChI
Affinity DataIC50: 443nMpH: 4.5 T: 2°CAssay Description:The assay was performed using a 96-well format on a HPLC equipped with four 96-well plate holders. Test compounds were preincubated with enzymes for ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2XD0ZXTPubMed